Sarr made 28 appearances for Strasbourg last season, playing in various competitions. He is a France U20 international and joined Strasbourg in August 2022, after moving from Olympique Lyon.

Mamadou Sarr is the son of Pape Sarr, a former Senegal national team player and midfielder for Lens. Strasbourg's coach, Liam Rosenior, has praised Sarr's skills, saying that he has the potential to become a world-class centre-half due to his temperament, athleticism, and ball control.